In pigs, genetic progress achieved by selection on prolificacy and merit carcass improvement has led to a rise in perinatal mortality, mostly due to a reduced piglet maturity. Piglet maturity acquisition and greatest fetal and placenta growth occur at the end of gestation (90-110 days of gestation, term at 114d) and result in a nutritional burden of pregnancy to the mother. Consequently, a fine balance of feto-maternal allocation of resource is necessary to support pregnancy. This regulation results from interactions between maternal and fetal genetic potential, maternal nutrition and environment, endometrial and placental functions. Recently, Workalemahu et al (2018) suggests that genetic influences are predominant in late gestation. Up to now, piglet survival is considered as a maternally influenced trait for genetic selection and the contribution of piglet genome seems underestimated. In this study, we investigated fetal genome (extreme purebreds and reciprocal crosses as actors of maturity processes) and sex influences on the expression of a subset of 40 imprinted genes during late gestation (90/110d) at the maternal interface (endometrium), using linear mixed models. First, we observed in endometrium, 18 differentially expressed genes (DEG) between 90 and 110 days of gestation. We also showed greater differential expression between Large White (LW: modern purebreds with less maturity) and Meishan (MS: rustic purebreds with greater maturity) at 90d (15 DEG) than 110d (5 DEG). Last, at 90d of gestation, fetal genome influenced the expression of five genes in LW endometrium associated to female fetuses and two genes in MS endometrium associated to male fetuses. Fetal sex influenced the expression of two genes in MS endometrium associated to MS purebred fetuses and six genes in LW endometrium associated to MSxLW crossed fetuses. The analyses did not identify fetal genome and sex effects on endometrium expression at 110d. In conclusion, our preliminary results showed that fetal genome or sex influenced the expression of some genes in endometrium at 90d of gestation. We observed a higher LW endometrium sensitivity to fetal environment than MS. This study suggested that fetal genome and particularly the paternal copy should contribute to piglet survival. This work was supported by INRA Animal Genetic department.