Nutritional quality of food as represented by the FSAm-NPS nutrient profiling system underlying the Nutri-Score label and cancer risk in Europe: Results from the EPIC prospective cohort study - Université Sorbonne Paris Nord Accéder directement au contenu
Article Dans Une Revue PLoS Medicine Année : 2018

Nutritional quality of food as represented by the FSAm-NPS nutrient profiling system underlying the Nutri-Score label and cancer risk in Europe: Results from the EPIC prospective cohort study

1 CRESS - U1153 - Equipe 3: EREN- Equipe de Recherche en Epidémiologie Nutritionnelle
2 Nutrition and Metabolism Section
3 Hôpital Avicenne [AP-HP]
4 Faculty of Medicine - School of Public Health [London, UK]
5 Department of Community Medicine, Faculty of Health Sciences
6 Cancer Registry of Norway
7 MEB - Department of Medical Epidemiology and Biostatistics
8 Genetic Epidemiology Group [Helsinki]
9 Department of Public Health, Section for Epidemiology
10 Danish Cancer Society Research Center
11 U1018 (Équipe 9) - Mode de vie, génétique et santé : études intégratives et transgénérationnelles
12 Division of Cancer Epidemiology
13 Department of Epidemiology
14 WHO Collaborating Center for Nutrition and Health, Unit of Nutritional Epidemiology and Nutrition in Public Health
15 Hellenic Health Foundation
16 Cancer Risk Factors and LifeStyle Epidemiology Unit
17 Epidemiology and Prevention Unit
18 Dipartimento di Medicina Clinica e Chirurgia
19 Cancer registry and histopathology unit
20 Unit of Cancer Epidemiology
21 DCD - Department for Determinants of Chronic Diseases
22 Department of Gastroenterology and Hepatology
23 School of Public Health - Department of Epidemiology and Biostatistics
24 Department of Social and Preventive Medicine, Faculty of Medicine
25 Julius Center for Health Sciences and Primary Care
26 Department of Nutrition [Oslo]
27 Public Health Directorate Asturias
28 Unit of Nutrition, Environment and Cancer
29 Facultat de Ciències de la Salut Blanquerna
30 Granada.ibs - Escuela Andaluza de Salud Publica
31 CIBERESP - Centro de Investigación Biomédica en Red de Epidemiología y Salud Pública = Consortium for Biomedical Research of Epidemiology and Public Health
32 Department of Epidemiology, Murcia Regional Health Council
33 Public Health Institute of Navarra
34 IdiSNA - Navarra Institute for Health Research / Instituto de Investigación Sanitaria de Navarra
35 Public Health Department of Gipuzkoa
36 Diabetes and Cardiovascular disease, Genetic Epidemiology
37 Nutritional Epidemiology
38 Department of Internal Medicine and Clinical Nutrition Institute of Medicine Sahlgrenska Academy
39 Department of Odontology
40 School of Clinical Medicine, Addenbrooke's Hospital
41 MRC Epidemiology Unit, Institute of Metabolic Science
42 Nuffield Department of Population Health - Cancer Epidemiology Unit
43 Department of Hygiene and Epidemiology
Inge Huybrechts
  • Fonction : Auteur
  • PersonId : 894802
Heather Ward
Cecilie Kyrø
Anja Olsen
Vittorio Krogh
Rosario Tumino
Carlotta Sacerdote
Emily Sonestedt
  • Fonction : Auteur
  • PersonId : 937851
Elio Riboli

Résumé

Background: Helping consumers make healthier food choices is a key issue for the prevention of cancer and other diseases. In many countries, political authorities are considering the implementation of a simplified labelling system to reflect the nutritional quality of food products. The Nutri-Score, a five-colour nutrition label, is derived from the Nutrient Profiling System of the British Food Standards Agency (modified version) (FSAm-NPS). How the consumption of foods with high/low FSAm-NPS relates to cancer risk has been studied in national/regional cohorts but has not been characterized in diverse European populations. Methods and findings: This prospective analysis included 471,495 adults from the European Prospective Investigation into Cancer and Nutrition (EPIC, 1992–2014, median follow-up: 15.3 y), among whom there were 49,794 incident cancer cases (main locations: breast, n = 12,063; prostate, n = 6,745; colon-rectum, n = 5,806). Usual food intakes were assessed with standardized country-specific diet assessment methods. The FSAm-NPS was calculated for each food/beverage using their 100-g content in energy, sugar, saturated fatty acid, sodium, fibres, proteins, and fruits/vegetables/legumes/nuts. The FSAm-NPS scores of all food items usually consumed by a participant were averaged to obtain the individual FSAm-NPS Dietary Index (DI) scores. Multi-adjusted Cox proportional hazards models were computed. A higher FSAm-NPS DI score, reflecting a lower nutritional quality of the food consumed, was associated with a higher risk of total cancer (HRQ5 versus Q1 = 1.07; 95% CI 1.03–1.10, P-trend < 0.001). Absolute cancer rates in those with high and low (quintiles 5 and 1) FSAm-NPS DI scores were 81.4 and 69.5 cases/10,000 person-years, respectively. Higher FSAm-NPS DI scores were specifically associated with higher risks of cancers of the colon-rectum, upper aerodigestive tract and stomach, lung for men, and liver and postmenopausal breast for women (all P < 0.05). The main study limitation is that it was based on an observational cohort using self-reported dietary data obtained through a single baseline food frequency questionnaire; thus, exposure misclassification and residual confounding cannot be ruled out. Conclusions: In this large multinational European cohort, the consumption of food products with a higher FSAm-NPS score (lower nutritional quality) was associated with a higher risk of cancer. This supports the relevance of the FSAm-NPS as underlying nutrient profiling system for front-of-pack nutrition labels, as well as for other public health nutritional measures.
Fichier principal
Vignette du fichier
journal.pmed.1002651.pdf (1.37 Mo) Télécharger le fichier
Origine : Fichiers éditeurs autorisés sur une archive ouverte
Loading...

Dates et versions

hal-02177559 , version 1 (10-07-2019)

Licence

Paternité

Identifiants

Citer

Mélanie Deschasaux, Inge Huybrechts, Neil Murphy, Chantal Julia, Serge Hercberg, et al.. Nutritional quality of food as represented by the FSAm-NPS nutrient profiling system underlying the Nutri-Score label and cancer risk in Europe: Results from the EPIC prospective cohort study. PLoS Medicine, 2018, 15 (9), pp.e1002651. ⟨10.1371/journal.pmed.1002651⟩. ⟨hal-02177559⟩
270 Consultations
49 Téléchargements

Altmetric

Partager

Gmail Facebook X LinkedIn More