A convenient synthetic route towards 1-hydroxymethylene-1,1- bis(H-phosphinates)
Résumé
A practical general route to 1-hydroxymethylene-1,1-bis(H-phosphinates) has been developed. Diverse alkyl or (hetero)aryl bisphosphinates were rapidly obtained in satisfying to excellent yields from corresponding acid chlorides and in situ generated bis(trimethylsilyl)phosphonite. This work is complementary to previous approaches. A generalisable procedure was optimised allowing the description of numerous compounds. To check the literature data, a pka value study was also performed.
Domaines
Chimie organique
Origine : Fichiers produits par l'(les) auteur(s)
Loading...